PGS, or preimplantation genetic screening, is a genetic test performed on embryos produced through IVF. PGS gives information about embryos’ genetic health to help your care team select the best embryo for transfer and improve your chance of achieving a successful pregnancy.
WHAT IS PRE-IMPLANTATION GENETIC SCREENING PGS?
Pre-implantation genetic screening PGS is a procedure in which the embryo is tested for the presence of any genetic diseases before it is transferred into the uterus. The embryos tested are obtained through the process of ICSI.
Pre-implantation genetic diagnosis PGD is a procedure in which the embryo is tested for the presence of specific known genetic diseases already diagnosed in the couple by karyotyping. The embryos tested are obtained through the process of ICSI. PGD is done on embryos tested to be normal in PGS
PGS and PGD helps to eliminate genetically abnormal embryos and helps to select and transfer disease free embryos into the uterus. Therefore, PGD increases the chances of successful pregnancy.
WHEN IS PGS RECOMMENDED?
- Couple whose multiple IVF cycles have been unsuccessful
- Advanced maternal age, more than 35-year-old
- Women having recurrent pregnancy loss
WHEN IS PGD RECOMMENDED?
- Couples who are carriers of single gene disorders/ chromosomal disorders/ sex linked genetic disorders
WHAT ARE THE ADVANTAGES OF PGD/PGS?
- PGD/PGS can check for the presence of various genetic diseases
- Couples who are carriers of genetic diseases have the advantage of choosing disease free embryos for implantation
WHAT ARE THE DISADVANTAGES OF PGD/PGS ?
- PGD/PGS significantly reduces the chances of placing a disease-free embryo, it does not completely eliminate the risk.
- In some cases, even though PGD/PGS is done, invasive testing may still be needed during the pregnancy
If you want to know more about PGD/PGS please feel free to contact us and make an appointment on 8885542910 to see the doctor